Women's Repair-4™ Program
A doctor-formulated, 28-day clinical protocol that restores a Lactobacillus-dominant vaginal microbiome. Eradicates Gardnerella biofilms, Candida overgrowth, and uropathogenic E. coli. Rebuilds via the gut-vaginal axis with oral and vaginal probiotics, then sustains hormonal balance with variant-specific support (a Vitex-led cycle support blend for premenopause, a TCM kidney-yin formula for postmenopause).
Vaginal dysbiosis is a gut-vaginal axis problem before it is a vaginal problem.
Recurrent BV, thrush, and UTIs are surface expressions of a deeper microbial and hormonal imbalance. Standard antibiotic-only treatment leaves 50-80% of women relapsing within 12 months because Gardnerella biofilms shield pathogens from both antibiotics and the immune system — and because antibiotics alone do nothing to rebuild the protective Lactobacillus community that prevents the next infection.
Three forces run in parallel. Pathogenic biofilms (Gardnerella, Candida, uropathogenic E. coli) persist on the vaginal epithelium. Gut-vaginal axis dysfunction depletes the Lactobacillus reservoir that normally translocates from gut to vagina via the perineum. And hormonal signalling — cyclic in premenopause, declining in postmenopause — disrupts the estrogen-glycogen-Lactobacillus pathway that maintains vaginal acidity.
This protocol addresses all three. Phase 1 eradicates pathogens and reinforces the gut barrier. Phase 2 rebuilds Lactobacillus via dual oral + vaginal delivery, holds vaginal pH with boric acid during recolonisation, and matches the right hormonal support to your life stage.
Four mechanisms. Twenty-eight days. Inside-out.
Endotoxin Containment + Gut Barrier Repair
Serum-derived bovine immunoglobulin (2.5g SBI, 1.1g IgG) + N-acetyl-D-glucosamine 1g
Bacterial endotoxins (LPS) leaking from a permeable gut drive systemic inflammation that disrupts the vaginal mucosa and undermines protective Lactobacillus. Serum-derived bovine immunoglobulins bind LPS directly in the gut lumen before it crosses into circulation. NAG reinforces the mucosal glycocalyx that seals the gut barrier. This is the foundation of the gut-vaginal axis.
Phase 1 — cut the inflammatory load undermining vaginal defence.
Urogenital Antimicrobial Support
Cherokee rose 93mg · China root 75mg · Japanese climbing fern 52mg (6 tablets daily)
Targeted Traditional Chinese Medicine antimicrobial formula for the urogenital tract. Cherokee rose acts as a urinary astringent. China root provides cystitis-targeting antimicrobial support. Japanese climbing fern delivers urinary sedative and antiseptic activity. Critical because uropathogenic E. coli colonises the vaginal introitus before ascending to the bladder — addressing both at once breaks the recurrence cycle.
Phase 1 — eradicate uropathogens at the urogenital interface.
Dual-Route Lactobacillus Recolonisation
Oral vaginal-targeted probiotic (L. crispatus + L. reuteri, 16B CFU) + vaginal probiotic suppository (L. rhamnosus + L. reuteri, 50B CFU) + boric acid pessary
L. crispatus is the most protective vaginal species — produces D- and L-lactic acid, hydrogen peroxide, and bacteriocins that maintain pH 3.8-4.5 and suppress pathogens. Oral delivery seeds the gut, then translocates to the vagina via the perineum. Direct vaginal delivery puts protective strains at the epithelium within hours. Boric acid maintains optimal pH during recolonisation and suppresses residual Gardnerella biofilms and azole-resistant C. glabrata.
Phase 2 — rebuild a Lactobacillus-dominant vaginal community.
Hormonal Adaptation — Variant-Specific
Premenopause: hormonal cycle support blend (Vitex 70mg + Vit B6 + Dong quai) · Postmenopause: TCM kidney-yin formula (Rehmannia 320mg + Cornus + Dioscorea + Ziziphus)
Hormonal balance is inseparable from vaginal microbiome health. For premenopausal women, a Vitex-led hormonal cycle support blend backs the estrogen-progesterone balance that drives the glycogen-Lactobacillus-lactic acid pathway. For postmenopausal women, a classical TCM kidney-yin formula addresses hot flushes, night sweats, sleeplessness, fatigue, and mild anxiety — supporting hormonal adaptation when ovarian estrogen has declined.
Phase 2 — match the hormonal stage that drives vaginal ecology.
Backed by the gut-vaginal axis.
From recurrent infections to a Lactobacillus-dominant microbiome.
Diagnostic test + Microbiome Doctor consult.
Complete your vaginal and gut microbiome tests. A Microbiome Doctor reviews your results, identifies which pathogens are elevated and which protective Lactobacillus are depleted, selects the right variant (Premenopause or Postmenopause) for your hormonal stage, and — where indicated — prescribes targeted antibiotics.
Eradication Phase.
Immunoglobulin powder binds gut endotoxins and reinforces the mucosal barrier. The TCM urogenital herbal blend targets uropathogens at the urogenital interface. Prescribed antibiotics — if your test results indicate them — clear identified pathogenic overgrowth. Expect mild changes in discharge, temporary urinary frequency, or mild bloating during this phase.
Rebuild Phase.
The oral vaginal-targeted probiotic seeds the gut-vaginal axis with L. crispatus and L. reuteri. The vaginal probiotic suppository delivers L. rhamnosus + L. reuteri directly to the epithelium. The boric acid pessary holds optimal pH (3.8-4.5) during recolonisation. Variant-specific hormonal support — the hormonal cycle support blend (Premenopause) or the TCM kidney-yin formula (Postmenopause) — runs alongside. Most patients notice improvement during this phase.
Maintain + Optional Extended RE-1.
Transition to your matching daily maintenance probiotic (Premenopause or Postmenopause) for a minimum of 6 months — Lactobacillus declines within 7-10 days of cessation without it. Dr Froomes strongly recommends extending the 500B CFU synbiotic for 4-12 weeks — patients who extend report the deepest, most sustained results.
Re-test your microbiome.
Repeat your vaginal and gut microbiome tests at the 6-month mark to objectively validate Lactobacillus dominance, confirm reduction in Gardnerella, Candida, and uropathogenic E. coli, and review your overall metabolic-microbial profile.
Questions, answered.
Who is this protocol for?
Adult women with recurrent bacterial vaginosis (BV), thrush (vulvovaginal candidiasis), urinary tract infections (UTIs), genitourinary syndrome of menopause (GSM), or other signs of vaginal microbiome disruption. Select Premenopause if you still have menstrual cycles — the program includes a hormonal cycle support blend (Vitex + B6 + Dong quai). Select Postmenopause if you have completed menopause — the program includes a TCM kidney-yin herbal formula for menopausal adaptation, hot flushes, and sleep.
Do I need a Microbiome Doctor consult before starting?
Strongly recommended. The Microbiome Doctor reviews your vaginal and gut microbiome test results, identifies elevated pathogens and depleted Lactobacillus species, selects the correct variant for your life stage, and — where indicated by test results — prescribes targeted antibiotics. The protocol is designed to work alongside clinical oversight rather than as a self-administered alternative.
Can I use the boric acid pessary if I'm pregnant or breastfeeding?
No. Boric acid pessaries must NOT be used during pregnancy or breastfeeding. If you are pregnant, planning pregnancy, or breastfeeding, consult your Doctor before starting this program — an alternative protocol may be appropriate.
Can I take the herbal supplements alongside HRT or oral contraceptives?
Vitex (in the hormonal cycle support blend) may affect hormonal medications including oral contraceptives. Some herbs in the TCM kidney-yin formula may not be compatible with hormone replacement therapy (HRT). If you are taking either HRT or hormonal contraception, inform your Microbiome Doctor before commencing Phase 2 — your Doctor will determine whether these herbal blends are appropriate or whether an alternative is needed.
Is discharge after inserting the pessary or probiotic normal?
Yes — this is expected as the capsule shell dissolves overnight. Wear a thin pad or panty liner to bed and the morning after. This is normal and indicates the product is working.
Can I have sex during the program?
Phase 1: vaginal intercourse is possible during Phase 1. Phase 2 (boric acid + probiotic phase): avoid vaginal intercourse or wait at least 12 hours after inserting the boric acid pessary. Insert the vaginal probiotic on nights without intercourse for best colonisation. Avoid oral contact with the vaginal area during the pessary phase — boric acid is toxic if ingested.
How long until I see results?
Most patients notice improvement in discharge, odour, and vaginal comfort during Phase 2 (days 15-28). UTI frequency and recurrent thrush typically improve over 4-8 weeks as Lactobacillus dominance is re-established. Patients who extend the 500B CFU synbiotic for 8-12 weeks consistently report the deepest, most sustained results across thousands of patients in Dr Froomes' practice.
What happens after the 28 days?
Transition to your matching daily maintenance probiotic (Premenopause or Postmenopause) — a daily probiotic + postbiotic that sustains Lactobacillus dominance. Lactobacillus declines within 7-10 days of cessation without maintenance support. The maintenance protocol is recommended for a minimum of 6 months, with a microbiome re-test at the 6-month mark to objectively validate progress.
Important — general advice only. Information presented on this page is general health information and is not personal medical advice. Always consult your treating practitioner before starting any new supplement.
Pregnancy: Boric acid pessaries must NOT be used if you are pregnant or breastfeeding. Vitex agnus-castus (in the hormonal cycle support blend) and some herbs in the TCM kidney-yin formula may affect hormonal medications including oral contraceptives and HRT. Consult your Microbiome Doctor for guidance if any of these apply.
Allergens: The immunoglobulin powder is derived from bovine sources — avoid if you have a dairy allergy (lactose intolerance is usually fine). Review allergen labels before starting.
Vaginal use only: Boric acid pessaries are for vaginal use only — do NOT take orally. Avoid oral contact with the vaginal area during Phase 2. Keep all vaginal products out of reach of children.
These products are listed complementary medicines and are not intended to diagnose, treat, cure, or prevent any disease. The Microbiome Clinic has no commercial affiliation with any specific supplement brand included in this protocol — supplements are selected on the basis of clinical evidence alone, in line with the Microbiome Clinic Independence Guarantee.